AIDS Weekly

HIV/AIDS & Tuberculosis - Mannose-binding lectin deficiency related to lower HIV and tuberculosis risk

HIV/AIDS HAART - HIV RNA suppression improved with three-drug/two-class regimen including efavirenz

HIV/AIDS HAART - Monocyte chemoattractant protein 1 mutated allele confers better response to protease inhibitors

HIV/AIDS HAART - Saquinavir lipid-based formulation improves bioavailability

HIV/AIDS Prognostics - CD4 percent predicts survival when CD4 count is 200-350 cells/mcL during HAART initiation

Amphotericin B Toxicity - Amphotericin B-related nephrotoxicity increases hospital stay in immunocompromised patients

Avian Influenza - NanoViricides president Anil Diwan presents details on H5N1 bird flu studies at conference

Business Update - U.S. FDA Advisory Panel recommends approval of RADIESSE for two facial aesthetic applications

Cardiovascular Research - Drug combination may reduce protease inhibitor-related hardening of the arteries

Clinical Trials - Starpharma initiates U.S. NIH-funded trial of microbicide for sexually transmitted diseases

HIV/AIDS & Herpes Simplex Virus - Oral HSV-2 reactivation often occurs on days of genital HSV-2 reactivation

HIV/AIDS Cardiovascular Risk - Heart disease risk factor prevalence decreased in HIV/AIDS patients in Switzerland

HIV/AIDS Diabetes - Abnormal glucose metabolism among HIV infected or at risk older men identified

HIV/AIDS Drug Adherence - Information-motivation-behavioral skills model conceptualizes HAART adherence determinants

HIV/AIDS Epidemiology - CD4 decline in Cape Town associated with increase in opportunistic infections

HIV/AIDS HAART - Antiretrovirals induce direct endothelial dysfunction

HIV/AIDS HAART - Efavirenz well tolerated in HIV/AIDS patients with preceding nevirapine-associated rash

HIV/AIDS HAART - Protease and RT gene polymorphisms in HIV-1 CRF02-AG subtypes not associated with HAART failure

HIV/AIDS Healthcare - Water quality improvement needed for persons with HIV/AIDS in South Africa

HIV/AIDS Neutropenia - Relative neutropenia exists in healthy black Zimbabwean infants

HIV/AIDS Pathogenesis - HIV SL9 variants bind to soluble HLA-A2 and to a particular soluble T cell receptor

HIV/AIDS Pathogenesis - Proviral integration within heterochromatin higher in HIV-2 than HIV-1 infection

HIV/AIDS Pathogenesis - SWI/SNF chromatin-remodeling complex is cofactor for Tat transactivation of HIV promoter

HIV/AIDS Peripheral Neuropathy - Peripheral neuropathy not associated with oxidant stress during NRTI-containing HAART

HIV/AIDS Pharmacogenetics - Pharmacogenetic characteristics determined among antiretroviral drugs in HIV/AIDS

HIV/AIDS Prevention - Cellegy announces results of committee review of Savvy Nigeria phase III HIV trial

HIV/AIDS Quality of Life - Predictors for lower quality of life among HAART users determined

HIV/AIDS Research - U.S FDA grants SPA for second phase 3 trial of HIV-associated lipodystrophy drug

HIV/AIDS Risk Reduction - Risk reduction counseling associated with decreased HIV transmission-associated behaviors

HIV/AIDS Stigma - Predictors of HIV-related stigma determined among young people living with HIV

HIV/AIDS Therapy - People with HIV/AIDS may migrate to obtain support and medical care

HIV/AIDS Therapy - Vical reports broad T cell immunity against HIV generated in vaccine phase I trial

HIV/AIDS Toxoplasmosis - Fulminant toxoplasmosis causes fatal pneumonitis and myocarditis in HIV/AIDS

HIV/AIDS Transmission - Some HIV-1 genotypes increase risk of HIV transmission by breast-feeding

HIV/AIDS Vaccine - HIV vaccine development hinges on public demand

HIV/AIDS Vaccine - Modestly positive interim data reported from Targeted Genetics' phase I HIV/AIDS vaccine trial

HIV/AIDS Vaccine - Multicomponent HIV vaccines constructed via assembly of HIV antigens on bacteriophage T4

HIV/AIDS-Related Infection - Oral HHV-8 shedding not predictive for development of Kaposi sarcoma lesions in HIV/AIDS

HIV/AIDS-Related Pneumonia -  Streptococcus pneumoniae nasopharyngeal carriage not related to S. aureus in HIV/AIDS

Hepatitis C Virus - Hepatitis C treatment rates and predictors clarified in HCV-HIV-coinfection

Mental Health - Depression and risky sex behavior are linked in African-American youth

Mental Health - Suicide is the third leading cause of death in Canada ahead of HIV/AIDS, diabetes and car accidents

Retrovirus Epidemiology - TRIM protein-mediated restriction of retroviral infection widespread among mammals

Vaginal Microbicides - Vaginal gel formulations vary with respect to spreadability