HIV/AIDS HAART
Monocyte chemoattractant protein 1 mutated allele confers better response to protease inhibitors
Published in AIDS Weekly, September 25th, 2006
"Antiretroviral drug efficacy has been widely studied in relation to viral factors. Mutations in the HIV coreceptors and their natural chemokines, however, may be critical in HIV infection and treatment response.
"We compared the efficacy of protease inhibitor (PI) treatment among PI-naive patients grouped according to whether they carried the chemokine CC motif receptor 2 (CCR-2) 64I and monocyte chemoattractant protein 1 (MCP-1)-2518G alleles," researchers in Spain report.
According to B. Coll...
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Source: AIDS Weekly (2006-09-25)
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