HIV/AIDS Pathogenesis
HIV depletes CCR5 cells in acute infection and maintains hyperactive state
Published in AIDS Weekly, October 2nd, 2006
According to a recent report from the United States, "The pathogenesis of chronic HIV infection has long been envisioned as a slow process of immune degradation ultimately leading to overt immune deficiency and AIDS.
"However, recent studies suggest that the massive viral replication of acute infection initiates the pathogenic process, significantly degrading the immune system and setting up a sequence of events that years later leads to final decompensation and AIDS."
"The central player of the disease process appears...
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Source: AIDS Weekly (2006-10-02)
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