HIV/AIDS Pathogenesis
Alpha-defensins within lymphoid tissues prevalent in HIV/AIDS and HIV-uninfected persons
Published in AIDS Weekly, October 16th, 2006
According to recent research from the United States, "Alpha-Defensins 1, 2, and 3 exert antiretroviral activity in vitro, but their role in controlling HIV-1 replication in vivo and the cells that produce them are controversial.
"This study sought to determine whether alpha-defensins are present in HIV-1-infected individuals' lymphoid tissues, the major site of HIV-1 replication, and to identify the cells that express them."
"a-Defensin expression was evaluated by immunostaining inguinal lymph...
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Source: AIDS Weekly (2006-10-16)
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