HIV/AIDS Adverse Drug Reaction
Hypokalemia is associated with tenofovir use in HIV/AIDS patients
Published in AIDS Weekly, October 30th, 2006
According to a recent report from the United States, "Although adverse events in HIV patients taking tenofovir are relatively rare, postmarketing reports of nephrotoxicity have alerted physicians to other potentially serious outcomes. We present a series of 40 patients who developed hypokalemia associated with tenofovir."
"Identified risk factors included concomitant ritonavir or didanosine use, a lower weight and longer duration of tenofovir use. Recovery or improvement was seen in the majority of patients (66%) after the discontinuation of tenofovir; however, four deaths occurred,"...
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Source: AIDS Weekly (2006-10-30)
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