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HIV/AIDS Therapy

Roche presents positive new data on Fuzeon and MK-0518

Published in AIDS Weekly, November 6th, 2006

New data presented at the 46th annual Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) in San Francisco indicate that nearly all treatment-experienced HIV patients who initiated therapy with Fuzeon (enfuvirtide) and the investigational integrase inhibitor MK-0518 in a clinical trial achieved undetectable levels of HIV (less than 400 copies per mL of blood).

Such response rates have never been attained in clinical trials of HIV patients living with drug-resistant virus. Fuzeon, co-developed by Roche and Trimeris (TRMS), is the first and only fusion inhibitor available for the treatment of HIV. MK-0518 is a novel investigational integrase inhibitor...

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