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HIV/AIDS

Reports from University of California, U.S., advance knowledge in HIV/AIDS research

Published in AIDS Weekly, January 15th, 2007

Reports from University of California, U.S., highlight recent research in HIV/AIDS.

Study 1: Recently published research from the United States has documented the inhibition of HIV-1 integrase (IN) activity by synthetic peptides derived from the HIV-1HXB2 Pol region of the viral genome.

"Peptides deriving from the HIV-1 HXB2 Pol gene sequence were evaluated for inhibitory activity against wild-type (WT) and mutant HIV-1 IN," wrote Z. Zawahir and colleagues, University of California.

"The most potent peptide corresponding to a region on the reverse transcriptase (RT) subunit of the Pol polyprotein showed IC50 value of 5...

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