HIV/AIDS Co-Infection Cell Biology
Study findings on HIV/AIDS co-infection cell biology are outlined in reports from Burnham Institute for Medical Research
Published in AIDS Weekly, February 26th, 2007
Researchers detail in "HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection," new data in HIV/AIDS co-infection. According to a study from the United States, "The chemokine receptors CCR5 and CXCR4 serve, in addition to CD4, as coreceptors for human immunodeficiency virus-1 (HIV-1), and infection with HIV-1 can cause dementia. In brain-derived cells, HIV-1 envelope glycoprotein gp120 initiates a signaling cascade that involves p38 mitogen-activated protein kinase and leads to neuronal cell death."
"Using mixed neuronal/glial cultures from rats and mice genetically deficient in one or both HIV...
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Source: AIDS Weekly (2007-02-26)
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