Gene Therapy

RNAi Shows Promise in Gene Therapy, Stanford Researcher Says

Published in AIDS Weekly, March 5th, 2007

Three years ago Mark Kay, MD, PhD, published the first results showing that a biological phenomenon called RNA interference could be an effective gene therapy technique. Since then he has used RNAi gene therapy to effectively shut down the viruses that cause hepatitis and HIV in mice.

With three human RNAi gene therapy trials now under way -- two in macular degeneration and one in RSV pneumonia -- the technique Kay pioneered may be among the first to find widespread use for treating human diseases. "We've worked on a gene therapeutic approach against viral hepatitis for about 10 years and this is the first thing we've done that really looks promising," said Kay,...

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Source: AIDS Weekly (2007-03-05)

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