HIV/AIDS
Research from University of Texas has provided new information about HIV/AIDS
Published in AIDS Weekly, May 14th, 2007
A report, "Antibodies to the superantigenic site of HIV-1 gp120: hydrolytic and binding activities of the light chain subunit," is newly published data in Molecular Immunology. "Antibodies (Abs) to the superantigenic determinant of HIV gp120 (gp120(SAg)) are potential protective agents against HIV infection. We report that the light chain subunits of Abs cloned from lupus patients using phage library methods bind and hydrolyze gp120(SAg) independent of the heavy chain," researchers in the United States report.
"Unlike frequent gp120(SAg) recognition by intact Abs attributable to V(H) domain structural elements, the isolated light chains expressed this activity...
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Source: AIDS Weekly (2007-05-14)
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