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HIV/AIDS

Study findings from Thomas Jefferson University, U.S., update HIV/AIDS knowledge

Published in AIDS Weekly, May 28th, 2007

New findings reported from Thomas Jefferson University, U.S., describe advances in HIV/AIDS.

Study 1: New investigation results, "Virion-associated uracil DNA glycosylase-2 and apurinic/apyrimidinic endonuclease are involved in the degradation of APOBEC3G-edited nascent HIV-1 DNA," are detailed in a study published in Journal of Biological Chemistry. According to a study from the United States, "Cellular cytidine deaminases APOBEC3 family is a group of potent inhibitors for many exogenous and endogenous retroviruses. It has been demonstrated that they induce G to A hypermutations in the nascent retroviral DNA, resulting from the cytosine (C) to uracil (U)...

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