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HIV/AIDS Therapy

Scientists at University of North Carolina, Division of Infectious Diseases describe research in HIV/AIDS therapy

Published in AIDS Weekly, June 4th, 2007

Researchers detail in "Triple-class antiretroviral drug resistance: risk and predictors among HIV-1-infected patients," new data in HIV/AIDS. "HIV-1 triple-class antiretroviral drug resistance (TC-DR) may substantially limit therapeutic options and compromise clinical outcomes. To estimate TC-DR prevalence and incidence, and identify risk factors for TC-DR acquisition," researchers in the United States report.

"We identified patients in the University of North Carolina HIV Cohort Study with TC-DR HIV-1 variants. Nucleos(t)ide reverse transcriptase inhibitor (NRTI), non-nucleoside reverse transcriptase inhibitor (NNRTI), and major protease inhibitor (PI) mutations, were...

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