HIV/AIDS Vaccines
Research from National Institute of Allergy and Infectious Disease yields new data on HIV/AIDS vaccines
Published in AIDS Weekly, June 18th, 2007
Current study results from the report, "Phase I clinical evaluation of a six-plasmid multiclade HIV-1 DNA candidate vaccine," have been published. According to recent research published in the journal Vaccine, "Needle-free delivery of a six-plasmid HIV-1 DNA vaccine encoding EnvA, EnvB, EnvC, and subtype B Gag, Pol, and Nef underwent open-label evaluation in 15 subjects; 14 completed the 0, 1, 2 month vaccination schedule. T cell responses to HIV-specific peptide pools were detected by intracellular cytokine staining of CD4(+) [13/14 (93%)] and CD8(+) [5/14 (36%)], and by ELISpot in 11/14 (79%)."
"Ten of 14 (71%) had ELISA antibody responses to Env proteins....
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Source: AIDS Weekly (2007-06-18)
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