HIV/AIDS
Data from Osaka University, Research Institute for Microbial Disease advance knowledge in HIV/AIDS
Published in AIDS Weekly, June 25th, 2007
Scientists discuss in "Retro-transduction by virus pseudotyped with glycoprotein of vesicular stomatitis virus" new findings in HIV/AIDS. "A virus pseudotyped with glycoprotein of vesicular stomatitis virus (VSV-G) can enter various cell types at a relatively high titer. We observed that the amount of viral antigen from VSV-G pseudotyped human immunodeficiency virus type 1 (HIV-1) producing cells was much higher than that from their non-pseudotyped counterparts," researchers in Osaka, Japan report.
"This enhanced viral antigen production was not observed when we used HIV-1 pol mutant, viral enzyme inhibitors, HIV Env protein, or VSV-G fusion defective mutants. The...
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Source: AIDS Weekly (2007-06-25)
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