HIV/AIDS

Drug warning prompts treatment changes for those infected with hepatitis B and HIV

Published in AIDS Weekly, July 2nd, 2007

Cross-resistance alarms raised earlier this year by Johns Hopkins researchers about a widely used antiviral therapy for hepatitis B liver infections have prompted swift treatment revisions by the drug’s maker and governmental agencies.

Findings by a team of Hopkins infectious disease specialists, to be published in the latest issue of The New England Journal of Medicine online June 21, showed that entecavir should not be used on its own in patients co-infected with HIV. Use of the drug led to cross-resistance to certain antiviral drugs used to treat the AIDS virus.

As a result of the study’s initial presentation in February at the 2007 Conference on...

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Source: AIDS Weekly (2007-07-02)

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