Nanotechnology
Investigators at Center for Cancer Research Nanobiology Program publish new data on nanotechnology
Published in AIDS Weekly, July 2nd, 2007
New investigation results, "Site-specific mutations in HIV-1 gp41 reveal a correlation between HIV-1-mediated bystander apoptosis and fusion/hemifusion," are detailed in a study published in Journal of Biological Chemistry. According to a study from the United States, "The loss of CD4(+) T cells in HIV-1 infections is hypothesized to be caused by apoptosis of bystander cells mediated by cell surface-expressed HIV-1 Env glycoprotein. However, the mechanism by which Env mediates this process remains controversial."
"Specifically, the role of HIV-1 gp120 binding to CD4 and CXCR4 versus the fusion process mediated by gp41 remains unresolved. Env-induced apoptosis in...
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Source: AIDS Weekly (2007-07-02)
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