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HIV/AIDS Immunology

Research from University of Pittsburgh in the area of HIV/AIDS immunology published

Published in AIDS Weekly, July 23rd, 2007

Research findings, "Human immunodeficiency virus (HIV-1) Vpr induced downregulation of NHE1 induces alteration in intracellular pH and loss of ERM complex in target cells," are discussed in a new report. According to a study from the United States, "Human immunodeficiency virus type 1 (HIV-1) Vpr is known to dysregulate host cellular functions through its interaction with cellular proteins. Using a protein array we assessed Vpr-mediated differential regulation of host cellular proteins expression."

"Results demonstrated that Vpr differentially regulated host factors that are involved in functions, such as cell proliferation, differentiation and apoptosis. One of the...

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