HIV/AIDS Immunology
Scientists at Seton Hall University, Department of Biological Sciences target HIV/AIDS immunology
Published in AIDS Weekly, August 27th, 2007
A new study, "Expression of the mu opioid receptor in the human immunodeficiency virus type 1 transgenic rat model," is now available. "Opioids, via the mc opioid receptor (MOR), can exacerbate bacterial infections and the immunopathogenesis of human immunodeficiency virus type 1 (HIV-1) infection. Recently, an HIV-1 transgenic (HIV-1Tg) rat model containing circulating HIV-1 gp120 was created," scientists writing in the Journal of Virology report.
"Using real-time reverse transcription-PCR, we found that MOR mRNA levels were significantly higher in the peritoneal macrophages of the HIV-1Tg rat than those in control animals. Lipopolysaccharide, a bacterial...
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Source: AIDS Weekly (2007-08-27)
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