HIV/AIDS

Researchers' work from University of Montreal focuses on HIV/AIDS

Published in AIDS Weekly, September 3rd, 2007

According to recent research from Montreal, Canada, "Human immunodeficiency virus type 1 (HIV-1) requires the sequential activities of virus-encoded proteins during replication. The activities of several host cell proteins and machineries are also critical to the completion of virus assembly and the release of infectious virus particles from cells."

"One of these proteins, the double-stranded RNA-binding protein Staufen1 (Stau1), selectively associates with the HIV-1 genomic RNA and the viral precursor Gag protein, pr55(Gag). In this report, we tested whether Stau1 modulates pr55(Gag) assembly using a new and specific pr55(Gag) oligomerization assay based on...

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Source: AIDS Weekly (2007-09-03)

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