HIV/AIDS

New HIV/AIDS research has been reported by J.M. Benito et al

Published in AIDS Weekly, September 3rd, 2007

"Hydroxyurea (HU) is a cytostatic drug which has been used as an anti-HIV agent due mainly to its synergistic activity when combined with certain anti-retrovirals. In addition, HU might have a beneficial effect on parameters involved in the pathogenesis of HIV infection, such as immune activation," scientists writing in the journal Clinical and Experimental Immunology report.

"To test this hypothesis, the effect of HU on T cell proliferation and T cell activation, as well as the potential association between these two phenomena, were examined in an in vitro model. HU exerted a dose-dependent anti-proliferative effect on T cells, and modulated the expression of...

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Source: AIDS Weekly (2007-09-03)

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