HIV/AIDS Therapy
Findings from Bristol-Myers Squibb Company provide new insights into HIV/AIDS therapy
Published in AIDS Weekly, September 17th, 2007
New research, "X-ray crystal structures of human immunodeficiency virus type 1 protease mutants complexed with atazanavir," is the subject of a report. According to a study from the United States, "Atazanavir, which is marketed as REYATAZ, is the first human immunodeficiency virus type 1 (HIV-1) protease inhibitor approved for once-daily administration. As previously reported, atazanavir offers improved inhibitory profiles against several common variants of HIV-1 protease over those of the other peptidomimetic inhibitors currently on the market."
"This work describes the X-ray crystal structures of complexes of atazanavir with two HIV-1 protease variants, namely, (i) an...
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Source: AIDS Weekly (2007-09-17)
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