HIV/AIDS

Data from Ohio State University provide new insights into HIV/AIDS

Published in AIDS Weekly, October 22nd, 2007

"'Molecular in situ-based assays are a useful adjunct to the diagnosis of viral infections by the surgical and cytopathologist. In some cases, the viral nucleic acids and/or proteins are abundant and easily detected by in situ hybridization or immunohistochemistry," researchers in the United States report.

"In other cases, such as the one integrated provirus typical of latent retroviral localization, in situ polymerase chain reaction amplification is required to localize the virus in the intact cell. Direct correlation of viral localization and the histologic changes will demonstrate in many cases that routine histopathology often does not provide sufficient information...

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Source: AIDS Weekly (2007-10-22)

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