HIV/AIDS
Research from Merck & Company, Inc. in the area of HIV/AIDS published
Published in AIDS Weekly, October 22nd, 2007
Data detailed in 'Determination of the HIV integrase inhibitor, MK-0518 (raltegravir), in human plasma using 96-well liquid-liquid extraction and HPLC-MS/MS' have been presented. "'An HPLC-MS/MS method was developed for the determination of MK-0518 (raltegravir), an HIV integrase inhibitor, in human plasma over the concentration range of 2-1000 ng/mL. Stable isotope labeled (13)C(6)-MK-0518 was used as an internal standard," scientists writing in the Journal of Chromatography B report.
"The sample preparation procedure utilized liquid-liquid extraction with hexane:methylene chloride in the 96-well format with a 200 microL plasma sample size. The compounds were...
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Source: AIDS Weekly (2007-10-22)
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