HIV/AIDS Therapy
New HIV/AIDS therapy findings from C. Ji and co-authors described
Published in AIDS Weekly, October 29th, 2007
A new study, 'Novel CCR5 monoclonal antibodies with potent and broad-spectrum anti-HIV activities,' is now available. According to a study from the United States, "'To identify monoclonal antibodies (mAbs) with high potency and novel recognition sites, more than 25,000 of mouse hybridomas were screened and 4 novel anti-human CCR5 mAbs ROAb12, ROAb13, ROAb14, and ROAb18 showing potent activity in cell-cell fusion (CCF) assay were identified. These mAbs demonstrated potent antiviral activities in both single-cycle HIV infection (IC(50) range: 0.16-4.3 microg/ml) and PBMC viral replication (IC(50) range: 0.02-0.04 microg/ml) assays."
"These potent antiviral effects were...
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Source: AIDS Weekly (2007-10-29)
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