HIV/AIDS
New HIV/AIDS study results from INSERM described
Published in AIDS Weekly, October 29th, 2007
Scientists discuss in 'PD-1 expression on human CD8 T cells depends on both state of differentiation and activation status' new findings in HIV/AIDS. "'OBJECTIVE AND PD-1 expression on HIV-specific CD8 T cells was recently reported to reflect functional exhaustion, resulting in uncontrolled HIV-1 replication. Assessing PD-1 expression on T cells may be highly relevant in T-cell immunology and vaccine monitoring," scientists in Paris, France report.
"However, this requires us to gain further insights into the significance of PD-1 expression on CD8 T cells in humans. We performed a detailed analysis of PD-1 expression pattern on various CD8 T cell subsets from healthy or...
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Source: AIDS Weekly (2007-10-29)
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