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HIV/AIDS

Study finds genetic influence on pace of HIV/AIDS progression

Published in AIDS Weekly, November 12th, 2007

What: Viral load—the amount of virus in the blood of an HIV-infected person—has long been viewed as the chief indicator of how quickly someone infected with HIV infection progresses to AIDS. New data published in Nature Immunology builds on previous work that suggests that several other factors in addition to viral load significantly contribute to disease progression rates.

Researchers led by Sunil Ahuja, M.D., of the University of Texas Health Science Center in San Antonio, examined genetic information from more than 3,500 HIV-1 infected and uninfected individuals. They found that individuals who had specific combinations of two genes—CCR5, which helps facilitate HIV...

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