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HIV/AIDS Vaccines

Researchers at University of Rochester have published new data on HIV/AIDS vaccines

Published in AIDS Weekly, November 19th, 2007

New research, 'HSV-1 amplicon vectors elicit polyfunctional T cell responses to HIV-1 Env, and strongly boost responses to an adenovirus prime,' is the subject of a report. "HSV-1 amplicon vectors elicit strong T-cell responses to encoded antigens but the qualitative nature of these responses is poorly understood. Antigen-specific CD4(+) and CD8(+) T-cell responses to amplicon and adenovirus (rAd5) vectors encoding HIV-1 gp120 were assessed following immunization of mice, by performing intracellular cytokine staining for IFNgamma, IL2 and TNF-alpha, following stimulation of splenocytes with a HIV-1 Env peptide pool," researchers in the United States report.

"The quality...

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