Published in AIDS Weekly, December 3rd, 2007
"Using this model, we altered the residues predicted to be exposed on the surface of this globular structure. Most of the alanine substitutions in these residues exerted little effect on the antiretroviral activity of human TRIM5c alpha(hu). or rhesus monkey TRIM5C alpha(rh). However, alteration of arginine 119 of TRIM5 alpha(hu). or the corresponding arginine...
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