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HIV/AIDS

Reports summarize HIV/AIDS research from J. Sheldon and co-authors

Published in AIDS Weekly, January 7th, 2008

According to recent research published in the Jaids - Journal of Acquired Immune Deficiency Syndromes, "Given the overlap between envelope and polymerase in the hepatitis B virus (HBV) genome, changes in antigenic sites of the HBV surface antigen may occur as a result of selection of drug-resistance mutations. Serum HBV-DNA was isolated from 71 patients with chronic hepatitis B receiving anti-HBV drugs for longer than 12 months, 52 of whom were HIV-positive."

"The reverse transcriptase/envelope gene from each HBV isolate was amplified using a nested polymerase chain reaction (PCR) covering 720 bp (aa 48 to 288), which includes all known nucleos(t)ide analogue...

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