HIV/AIDS

Research reports from Catholic University provide new insights into HIV/AIDS

Published in AIDS Weekly, January 21st, 2008

"Consensus on the interpretation of mutations in the human immunodeficiency virus (HIV)-1 reverse transcriptase (RT) gene that predict the response to didanosine treatment is needed. Baseline HIV-1 RT genotypes and 12-week virological outcomes for patients undergoing didanosine-containing salvage regimens were extracted from prospective studies," researchers in Rome, Italy report.

"Existing didanosine genotypic-resistance interpretation rules were validated in the entire-patient data set. Mutations were given weighted positive or negative scores according to their coefficient of correlation with virological response in a derivation set. The score resulting from the...

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Source: AIDS Weekly (2008-01-21)

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