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HIV/AIDS Therapy

New HIV/AIDS therapy study findings reported from Yale University, Department of Pharmacology

Published in AIDS Weekly, January 28th, 2008

A report, 'Intracellular metabolism and persistence of the anti-human immunodeficiency virus activity of 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine, a novel thymidine analog,' is newly published data in Antimicrobial Agents and Chemotherapy. According to a study from the United States, "The therapeutic benefits of current antiretroviral therapy are limited by the evolution of drug-resistant virus and long-term toxicity. Novel antiretroviral compounds with activity against drug-resistant viruses are needed. 2',3'-didehydro-3'-deoxy-4'-ethynylthymidine (4'-Ed4T), a novel thymidine analog, has potent anti-human immunodeficiency virus (HIV) activity, maintains considerable activity...

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