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Simian Immunodeficiency Virus

Reports summarize simian immunodeficiency virus research from Baylor College of Medicine

Published in AIDS Weekly, February 4th, 2008

Scientists discuss in 'Changes in simian immunodeficiency virus reverse transcriptase alleles that appear during infection of macaques enhance infectivity and replication in CD4+ T cells' new findings in simian immunodeficiency virus. According to recent research from the United States, "We previously showed that a slowly replicating, minimally pathogenic clone of simian immunodeficiency virus (SIV), SIVmneCl8, evolves increased ability to replicate in T cells with the onset of AIDS in pig-tailed macaques. Moreover, molecular clones derived from late stages of infection (SIVmne170 and SIVmne027) replicate to high levels in vivo compared to SIVmneCl8."

"Here, we...

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