Published in AIDS Weekly, February 4th, 2008
"In healthy subjects, monocytes differentiate into CD1a(+) DCs in the presence of granulocyte macrophage colonystimulating factor and interleukin (IL)-4 and matured in the presence of lipopolysaccharide. Here, we found that in 30% and 45% of HIVinfected white and African subjects, respectively, monocytes gave rise to a homogeneous CD1a(-) DC population. In the...
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