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HIV/AIDS

Reports outline HIV/AIDS research from J.V.R. Madruga and colleagues

Published in AIDS Weekly, February 4th, 2008

According to a study from the United States, "Study 903 is a phase 3 trial with a completed 144-week, double-blind phase comparing tenofovir DF (TDF) with stavudine (d4T), in combination with lamivudine (3TC) and efavirenz (EFV), and an ongoing 336-week open-label extension phase. Patients in 3 countries completing the d4T treatment phase were allowed to switch d4T to TDF and receive once-daily TDF+3TC+EFV in the extension phase."

"At the time of switch, 100% and 99% of patients (n = 85; 60% male, 64% White; mean age 37 years; mean CD4 = 650 celIS/MM3) had HIV RNA < 400 and < 50 copies/mL. At 144 weeks after the switch, 89% (missing = failure) had HIV RNA < 400...

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