HIV/AIDS
HIV persists in the gut despite long-term HIV therapy
Published in AIDS Weekly, February 25th, 2008
Even with effective anti-HIV therapies, doctors still have not been able to eradicate the virus from infected individuals who are receiving such treatments, largely because of the persistence of HIV in hideouts known as viral reservoirs. One important reservoir is the gut, where HIV causes much of its damage due to the large number of HIV target cells that reside there. These cells, known as CD4+ T cells, are largely contained in lymph nodes and patches of lymphocytes that collectively are called gut-associated lymphoid tissue, or GALT.
Because of the importance of the gut to HIV disease, scientists hoped that long-term treatment with antiretroviral drugs could...
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Source: AIDS Weekly (2008-02-25)
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