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HIV/AIDS

Imitating monkey's 'jumping genes' could lead to new treatments for HIV

Published in AIDS Weekly, March 3rd, 2008

UCL (University College London) scientists have taken a significant step in understanding how retroviruses such as HIV can move between species and the biological mechanisms behind the ‘jumping genes’ which make some monkeys immune. They will now use this knowledge to develop a gene therapy treatment for HIV/AIDS in humans.

The international team of researchers, coordinated by Professor Greg Towers, UCL Infection and Immunity, and funded by the Wellcome Trust, have identified a combination of genes in a species of monkey that protects against retroviruses – a particularly opportunistic family of viruses that can integrate into the host’s genome and replicate as part of...

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