HIV/AIDS Risk Factors
Investigators at Tibotec zero in on HIV/AIDS risk factors
Published in AIDS Weekly, March 31st, 2008
Research findings, 'Drug interactions between HIV protease inhibitors and acid-reducing agents,' are discussed in a new report. "Maximal efficacy of protease inhibitor-based antiretroviral therapy for HIV/AIDS requires adequate drug absorption and bioavailability. However, the use of acid-reducing agents in patients treated with highly active antiretroviral therapy is common and may induce clinically significant drug-drug interactions that alter plasma protease inhibitor concentrations, which may lead to inadequate viral suppression or adverse events," investigators in the United States report.
"As plasma antiretroviral concentrations are not routinely monitored in...
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Source: AIDS Weekly (2008-03-31)
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