HIV/AIDS

Recent findings from P. Cahn and co-authors highlight research in HIV/AIDS

Published in AIDS Weekly, April 7th, 2008

According to a study from the United Kingdom, "This study aimed to investigate the multiple-dose pharmacokinctics of apricitabine, a novel deoxycytidine analogue reverse transcriptase inhibitor, in antiretroviral-naive patients with HIV-1 infection. This was an international, randomized, double-blind, placebo-controlled, multicentre, dose-ranging study."

"Patients received 10 days' oral placebo or apricitabine 200,400, 600 or 800 mg twice daily or 800 or 1200 mg once daily. On days 1 and 8, blood and urine samples were collected over 24 hours for pharmacokinetic analysis. Apricitabine triphosphate pharmacokinetics were investigated in peripheral blood mononuclear cells...

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Source: AIDS Weekly (2008-04-07)

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