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HIV/AIDS Therapy

Data on HIV/AIDS therapy reported by researchers at University of North Carolina

Published in AIDS Weekly, April 21st, 2008

Fresh data on HIV/AIDS are presented in the report 'The pharmacokinetics and viral activity of tenofovir in the male genital tract.' "To measure tenofovir (TFV) concentrations in the male genital tract (GT) after single and multiple doses of tenofovir disoproxil fumarate (TDF) and evaluate the HIV-1 RNA response to monotherapy. A pharmacokinetic study of blood plasma (BP) and GT TFV concentrations in 9 men was conducted after 1 and >or=14 doses of TDF," scientists in the United States report.

"TFV concentrations were measured by validated high-performance liquid chromatography-ultraviolet or tandem mass spectrometry methods, and HIV-1 RNA was measured using Roche...

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