Published in AIDS Weekly, May 12th, 2008
"Coadministration of LPV/RTV reduces the clearance of CPT11 by 47% (11.3 +/- 3.5 vs 21.3 +/- 6.3 l/h/m(2), P = 0.0008). This effect was associated with an 81% reduction (P = 0.02) of the AUC (area under the curve) of the oxidized metabolite APC...
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