Published in AIDS Weekly, May 12th, 2008
"They were obtained by Sonogashira reaction, 'click' chemistry or Pd-catalyzed oxidative coupling. The iodo precursor 5 turned out as a potent compound against wild type and mutated HIV-1 virus," wrote K. Danel and colleagues.
The researchers concluded: "All dimeric compounds showed lower activity against HIV-1 than MKC-442, except the...
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