HIV/AIDS Therapy
Research from National Cancer Institute reveals new findings on HIV/AIDS therapy
Published in AIDS Weekly, May 19th, 2008
Investigators publish new data in the report 'Immune activation driven by CTLA-4 blockade augments viral replication at mucosal sites in simian immunodeficiency virus infection.' According to a study from the United States, "The importance of chronic immune activation in progression to AIDS has been inferred by correlative studies in HIV-infected individuals and in nonhuman primate models of SIV infection. Using the SIV(mac251) macaque model, we directly address the impact of immune activation by inhibiting CTLA-4, an immunoregulatory molecule expressed on activated T cells and a subset of regulatory T cells."
"We found that CTLA-4 blockade significantly increased T...
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Source: AIDS Weekly (2008-05-19)
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