Antiretrovirals

Study data from University of Rochester update knowledge of antiretrovirals

Published in AIDS Weekly, June 30th, 2008

According to a study from the United States, "To evaluate the antiretroviral activity of antiretroviral agents and to compare the effects of two different antiretroviral agents, we propose a non-parametric mixed-effects model to investigate change of CD4+ counts."

"The proposed model and methods are applied to analyse the data from PACTG345 study. Population and individual patterns of change of CD4+ counts and a reference band are obtained," wrote H. Liang and colleagues, University of Rochester.

The researchers concluded: "Our results indicate that treatment with high-dose ritonavir is significantly superior compared with low-dose ritonavir."

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Source: AIDS Weekly (2008-06-30)

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