HIV/AIDS
Research in the area of HIV/AIDS reported from National Institutes of Health
Published in AIDS Weekly, June 30th, 2008
"Human immunodeficiency virus type 1 (HIV-1) infection has been associated with perturbations of plasmacytoid dendritic cells (PDC), including diminished frequencies in the peripheral blood and reduced production of type I interferons (IFNs) in response to in vitro stimulation. However, recent data suggest a paradoxical increase in production of type 1 interferons in vivo in HIV-infected patients compared to uninfected controls," scientists in the United States report.
"Using a How cytometric assay to detect IFN-alpha-producing cells within unseparated peripheral blood mononuclear cells, we observed that short-term interruptions of antiretroviral therapy are sufficient...
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Source: AIDS Weekly (2008-06-30)
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