HIV/AIDS
Studies from University of Alabama yield new data on HIV/AIDS
Published in AIDS Weekly, June 30th, 2008
"Accurate identification of the transmitted virus and sequences evolving from it could be instrumental in elucidating the transmission of human immunodeficiency virus type 1 (HIV-1) and in developing vaccines, drugs, or microbicides to prevent infection. Here we describe an experimental approach to analyze HIV-1 env genes as intact genetic units amplified from plasma virion RNA by single-genome amplification (SGA), followed by direct sequencing of uncloned DNA amplicons," investigators in the United States report.
"We show that this strategy precludes in vitro artifacts caused by Taq-induced nucleotide substitutions and template switching, provides an accurate...
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Source: AIDS Weekly (2008-06-30)
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