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HIV/AIDS

Findings from University of Ghent broaden understanding of HIV/AIDS

Published in AIDS Weekly, July 7th, 2008

"Maraviroc (Pfizer's UK-427857, Selzentry or Celsentri outside the US) is the first agent in the new class of oral HIV-1 entry inhibitors to acquire FDA and EMEA approval," researchers in Ghent, Belgium report.

"It is expected that this drug will be effective only in a subpopulation of HIV-1-infected people, namely those harbouring only the R5 virus. The wide use of this drug is currently hampered by the lack of a readily available R5 virus only determination test (tropism test) and by insufficient scientific insight into the dynamics of R5 and X4 viruses during infection," wrote L. Vandekerckhove and colleagues, University of Ghent.

The researchers...

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