HIV/AIDS Immunology
Scientists at Tokyo Medical and Dental University target HIV/AIDS immunology
Published in AIDS Weekly, July 14th, 2008
New investigation results, 'Statin-induced inhibition of HIV-1 release from latently infected U1 cells reveals a critical role for protein prenylation in HIV-1 replication,' are detailed in a study published in Microbes and Infection. "Latent infection of human immunodeficiency virus type 1 (HIV-1) represents a major hurdle in the treatment of acquired immunodeficiency syndrome (AIDS) patients. Statins were recently reported to suppress acute HIV-1 infection and reduce infectious virion production, but the precise mechanism of inhibition has remained elusive," researchers in Tokyo, Japan report.
"Here we demonstrate that lypophilic statins suppress HIV-1 virion...
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Source: AIDS Weekly (2008-07-14)
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