HIV/AIDS Co-Infection

New findings in HIV/AIDS co-infection described by S.N. Pawar and co-researchers

Published in AIDS Weekly, July 28th, 2008

According to recent research from the United States, "Factors explaining why human immunodeficiency virus ( HIV) enhances the risk of reactivated tuberculosis ( TB) are poorly understood. Unfortunately, experimental models of HIV-induced reactivated TB are lacking."

"We examined whether cynomolgus macaques, which accurately model latent TB in humans, could be used to model pathogenesis of HIV infection in the lungs and associated lymph nodes. These experiments precede studies modeling the effects of HIV infection on latent TB. We infected two groups of macaques with chimeric simian - human immunodeficiency viruses ( SHIV-89.6P and SHIV-KU2) and followed viral titers and...

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Source: AIDS Weekly (2008-07-28)

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