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Massachusetts General Hospital

Growth hormone reduces abdominal fat, cardiovascular risk in HIV patients on antiviral therapy

Published in AIDS Weekly, August 18th, 2008

Low-dose growth hormone treatment reduced abdominal fat deposits and improved blood pressure and triglyceride levels in a group of patients with HIV lipodystrophy, a condition involving the redistribution of fat and other metabolic changes in patients receiving combination drug therapy for HIV infection. However, growth hormone treatment appeared to increase blood glucose levels, particularly in those already exhibiting glucose intolerance. The study from researchers at Massachusetts General Hospital (MGH) appears in the Aug.. 6 Journal of the American Medical Association, a special issue on HIV/AIDS.

"This study tells us that a rationally dosed growth hormone regimen...

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