HIV/AIDS
Researchers' work from INSERM focuses on HIV/AIDS
Published in AIDS Weekly, September 15th, 2008
"Blood-circulating monocytes migrate in tissues in response to danger stimuli and differentiate there into two major actors of the immune system: macrophages and dendritic cells. Given their migratory behavior and their pivotal role in the orchestration of immune responses, it is not surprising that cells of the monocyte lineage are the target of several viruses, including human immunodeficiency virus type 1 (HIV-1)," researchers in Lyon, France report.
"HIV-1 replicates in monocytoid cells to an extent that is influenced by their differentiation status and modulated by exogenous stimulations. Unstimulated monocytes display a relative resistance to HIV infection mostly...
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Source: AIDS Weekly (2008-09-15)
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